Nucleotides are most commonly known as the building blocks of DNA and RNA. The DNA molecule consists of nucleotides in which the sugar component is deoxyribose and the RNA molecule consists of nucleotides in which the sugar is ribose. In addition, they also have important regulatory functions in cell metabolism. For example, nucleotides are able to provide energy for non-spontaneous reactions (such as the hydrolysis of ATP to ADP) and to perform signal transduction (cAMP).

They are also part of important coenzymes, such as coenzyme A, FAD, riboflavin-5'-phosphate and NADP+.  
 
The most common nucleotides are divided into two groups, called purines and pyrimidines, based on the structure of their nitrogenous bases. In DNA, the purine bases include adenine (A) and guanine (G), while the pyrimidine bases are thymine (T) and cytosine (C). RNA includes adenine, guanine, cytosine and uracil (U) instead of thymine. Thymine is produced by adding a methyl group to uracil.
 

Our current modern diet contains nucleotides in low levels, with low bioavailability. More than 80% of the nucleotides that come from food are of the purine form. This means that a deficiency of nucleotides in the diet is generally in the pyrimidine form. The absorption of nucleotides from food is limited because nucleic acids are well protected in the cells. 
Absorption from food amounts to only 5-15%. Supplemented nucleotides that are freely (unprotected) available have a much better absorption in the intestine. Their absorption level is 80-90%.
 
There are four ways the body can obtain the nucleotides: newly composed in the body from amino acids or glucose, rescued from the breakdown of the body's own DNA and RNA, absorbed from the diet, or in the form of a nutritional supplement.
 
Nutri-tide®NT is a unique product. It ensures a balanced supply of nucleotides to the destination site. It contains both pyrimidine and purine bases.